Ibuprofen is a non-steroidal anti-inflammatory medication commonly used in human beings as a painkiller and to decrease fever. It is readily available in many non-prescription formulas (Advil, Motrin, Midol) along with in prescription strength medications. Though fairly safe for people, ibuprofen can be harmful for dogs and has a reasonably narrow margin of safety, indicating that it is safe for dogs only within an extremely narrow dosage range.
What Is Ibuprofen and Naproxen Toxicity?
Ibuprofen is the active ingredient in medications like Advil and Nuprin. Naproxen resembles ibuprofen but is longer-acting; it is the active ingredient in medications like Aleve and Naprosyn. Ibuprofen and naproxen are extensively used to treat pain, fever, and inflammation in individuals. Sadly, these drugs can be very poisonous (dangerous) to cats and dogs. Toxicity takes place when a cat or dog eats enough of one of these drugs to cause destructive impacts in the body.
The damaging effects of ibuprofen or naproxen in animals include hindering blood circulation to the kidneys and hindering the production of substances that help safeguard the inner lining of the stomach. For that reason, toxic effects of ibuprofen and naproxen in dogs and cats consist of kidney damage that can lead to kidney failure and severe stomach irritation that can progress to stomach ulcers.
- A single 200-milligram ibuprofen tablet can be harmful to a cat or small- to medium-sized dog; harmful impacts can take place rapidly and harm the kidneys and stomach.
- Never ever administer human medications to your family pet unless advised to do so by your vet, and keep all medications in the home protected to assist prevent unexpected swallowing by family pets.
- Ibuprofen and naproxen can be hazardous to dogs and cats, however cats are a lot more susceptible to this toxicity than dogs are.
- Ibuprofen and naproxen are drugs meant for humans that should not be provided to animals.
How Does Toxicity Occur?
Numerous cases of ibuprofen and naproxen toxicity in dogs and cats are unintentional. An animal might discover and chew on a bottle of pills or eat a pill that has fallen on the floor. Because these drugs are so potent, a single 200-milligram ibuprofen tablet can be poisonous to a cat or small- to medium-sized dog.
Unfortunately, some cases of toxicity take place since family pet owners offer human medication to their family pet without being advised to do so by a veterinarian. Ibuprofen and naproxen are planned for human use and needs to not be given to pets.
Ibuprofen for Dogs Overdose: What Are the Clinical Signs of Ibuprofen and Naproxen Toxicity?
When swallowed, ibuprofen and naproxen are rapidly taken in from the stomach and intestines. Depending on the quantity of drug consumed, poisonous effects can occur within an hour, but some signs can take a couple of days to appear. The most common side effect is stomach inflammation. In moderate cases, this may cause vomiting. In severe cases, it can cause the animal to vomit blood; the inflammation can likewise be severe enough to cause stomach ulcers and stomach perforations (leaks in the stomach wall that allow stomach acid to leak into the abdominal area). If stomach bleeding is severe, blood transfusions may be essential to conserve the patient.
Ibuprofen and naproxen toxicity can likewise prevent blood circulation to the kidneys, which can cause kidney failure. Exceptionally high poisonous doses of these drugs can also affect the brain, causing modified psychological status, seizures, and coma. Other clinical signs connected with toxicity can consist of the following:
- Cravings loss.
- Abdominal pain.
- Pale gums (secondary to blood loss).
- Vomiting (in some cases with blood).
- Diarrhea (might be darker in color due to absorbed blood).
How Is Ibuprofen and Naproxen Toxicity Diagnosed?
Diagnosis of ibuprofen and naproxen toxicity is typically based on a history of current swallowing of one of these drugs. Your veterinarian may advise diagnostic testing, such as blood work (a chemistry panel and total blood cell count [CBC] and urinalysis to assess the level of the damage. If stomach perforation or kidney failure are presumed, additional diagnostic screening is required.
What Are the Treatment and Outcome for Ibuprofen and Naproxen Toxicity in Dogs and Cats?
Ibuprofen and naproxen are soaked up by the body very rapidly. If swallowing is recognized immediately, vomiting can be caused to eliminate the drug from the stomach prior to the body can absorb it. Another option might be to sedate the animal to eliminate the contents of the stomach. Your vet may likewise administer a special preparation of liquid-activated charcoal to slow absorption of product from the stomach and intestines. This step might need to be repeated every couple of hours, as these medications have a long-lasting effect.
There is no specific antidote for ibuprofen or naproxen toxicity. Treatment might include intravenous fluid therapy, blood transfusions, medications to assist heal stomach damage, and other medications to help support and stabilize the patient. Hospitalization may be needed so that blood values, urine output, and essential signs can be monitored. Ibuprofen or naproxen toxicity can be fatal. Nevertheless, animals can endure if the condition is recognized, identified, and treated quickly. The amount of drug included also has a direct effect on recovery and long-lasting result.
Most cases of ibuprofen or naproxen toxicity are avoidable. Never ever administer human medications to your pet unless instructed to do so by your veterinarian, and keep all medications in the home protected to assist avoid unexpected swallowing.